Novotech Nano Crystalline Bioactive Calcium Hydroxyapatite

Product #: 2014 HA

Novotech has developed a new proprietary method for the production of nano-sized hydroxyapatite (HA) utilizing low cost raw materials and an environmentally safe acid-free process. Novotech’s is a white powder with 70 – 150 nm particle size that has a high degree of bio compatibility with living tissues.

Specification

TYPICAL PROPERTIES VALUE
CAS 12167-74-7
EC Number 235-330-6
Appearance CAS White
Molecular Formula Ca10(PO4)6(OH)2
Molecular Weight 1004
Hydroxyapatite (HA) Ca/P ionic ratio 1.67
Average particle size 70-150 nm
Density 3.34 (g/cc)
Bulk density 190 g/L
Crystal form Cubic
BET Surface Area 25.97 (m2/g)
Melting Point 1650°C
PHASE COMPOSITION BY XRD
Phase Sample (%)
Hydroxyapatite 100
Calcium Oxide (CaO) Not Detected
α-Tricalcium phosphate (α-TCP) Not Detected
β-Tricalcium phosphate (β-TCP) Not Detected
Tetracalcium phosphate (TTCP) Not Detected
Results in relative weight percen
CHEMICAL ANALYSIS Ca10(PO4)6OH2
Element Sample (%) Element Sample (%)
Al 0.09 Na 0.14
Ca 36.97 P 16.94
Fe 0.03 Si 0.11
K 0.02 Sr 0.01
Mg 0.20 Ti <0.01

Other elements tested (<0.01%): Ag, As, Au, B, Ba, Be, Bi, Cd, Ce, Co, Cr, Cu, In, Li, Mn, Mo, Nb, Ni, Pb, Pd, Pt, Sb, Se, Sn, Ta, Te, Tl, V, W, Zn & Zr.
 Results in weight percent unless otherwise indicated. Method(s): CAP-017P (ICP-AES).

XRD Diffraction of the Hydroxyapatite along with matching patterns from ICDD library of standards.

Hydroxyapatite nano crystalline bioactive
Hydroxyapatite nano crystalline bioactive
Hydroxyapatite nano crystalline bioactive

Applications

Cosmetics

  • For skin care products- eyeshadow & mascara, lipstick & lip glosses, blushers & bronzers.

Cosmetology

  • Calcium hydroxyapatite based products intended to: rejuvenate the skin, increase the volume of tissue, face beauty masks, eliminate skin blemishes and for use with injections in plastic surgery.

Stomatology

  • Calcium phosphate bone cements for sealing root canals. Components for the regeneration and remineralization of dental enamel (in the form of powder, gel or toothpaste that specifically formulated to prevent the formation of dental caries and reduce tooth sensitivity.

Food Additives

  • Ingredients used in sports drinks, milk powder, fish and minced meat, alcoholic beverages, herbal teas, dry and semi-dry breakfast cereals, fast food, confectionery products and additives for animal feeds. Supplements with easily digestible calcium to treat calcium deficiencies.

Biologically Active Additives (BAA)

  • Components of dietary supplements for the prevention and treatment of osteoporosis (capsules and tablets for regulating the calcium balance in humans of any age). For products that prevent bone tissue resorption, maintain posture, reduce the risk of bone fractures and dental caries. Also admitted as part of vitamins and drugs like calcium-containing supplements for humans and animals.

Bioceramics

  • For medical implants (endo-implants, porous inserts and for coatings on titanium implants). Also useful as a premix for bone tissue regeneration (ceramic beads, porous implants, bone cements, gels, suspension and injectables for bone regeneration etc.).